Making Assays FAIR
Overcoming Barriers to the Adoption of Human Alternatives to Animals in Biomedical Research FAIR data is data that is findable, accessible, interoperable, and reusable. Well, maybe it’s time for FAIR…
A recent paper from NTP showcases the application of mechanism-based NAMs for prediction of cardiotoxic potential. In a previous post, Getting Back on Track with NAMs at FDA, we encouraged…
Excipients are the “fillers” in formulated drugs. They are included to ensure long term storage, stabilize or promote delivery of the active drug. Excipients are assumed by many to be…
The ToxCast program of the US EPA was initiated over a decade ago. Its goal was to find rapid and efficient methods to prioritize thousands of chemicals for potential human health…
Many drugs can cause adverse effects on the cardiovascular system. Oncology drugs including targeted kinase inhibitors are particularly problematic. Cardiovascular toxicities present in the clinic as high blood pressure, cardiac…