Alto Predict https://validator.w3.org/feed/docs/rss2.html Biomarker in the Spotlight: VCAM-1 Welcome to Alto Predict! Privileged Chemistry, Privileged Biology – Made for Each Other Best Practices for Chemical Probes Mouse Vs Man – The Importance of Human-Based Approaches in Biomedical Research Are you ready for it? Technology readiness for in vitro NAMs Phenotypic Screening – Advancing the Science Recent Updates to EPA’s ToxCast Program – and Why We Care Catalyzing change at the NIH with Novel Alternative Methods NAMs on the NIH Roadmap About Making Assays FAIR Expertise CHITA – a registry of in vitro NAMs Let’s Talk About Validation! Roadmap to Precision Medicine: Role of Human In Vitro Translational Assays Machine Learning & AI in Drug Discovery IDO Inhibitors – No Go for IO? Modernizing How FDA Manages Drug Substance Information Engineering in Biology Mapping Pathways in Phenotypic Assays Using Chemical Probes Challenging Assumptions About ‘Inactive Ingredients’ Chemical Toxicity Mechanisms: Revisiting ToxCast Data Diverse Mechanisms of Cardiovascular Toxicity Getting Started with FAIR Choosing the Right Cell Type Designing Physiologically Relevant Assays Finding the Right Assay Conditions Assay Endpoints – Measure What Matters Chain of Translatability Coronavirus and Thrombosis Getting Back on Track with NAMs at FDA Cardiotoxicity Risk – A Step in the Right Direction Assay Validation – Are We There Yet? Unlocking the Value of Research Data Ontology Basics Things I Wish I Knew – Building a Platform Company Is the Scientific Paper Obsolete? AI in Drug Discovery – Why We Are Not There Yet Persistence and Resilience FAIR Bioassay Metadata from the Data FAIRY Can Network Biology Fuel Innovation in Drug Discovery? The Alto Predict Project Discovery Program Outcome Pathways Home Tips for Aspiring Drug Discoverers Phenotypic Platforms are Taking Over Drug Discovery Nuisance Compounds I Have Known Making an Impact on Hit Triage Blog